What have we learned from SHIVA?
Author:
Publisher
Springer Science and Business Media LLC
Subject
Oncology
Link
http://www.nature.com/articles/nrclinonc.2016.164.pdf
Reference10 articles.
1. Le Tourneau, C. et al. The spectrum of clinical trials aiming at personalizing medicine. Chin. Clin. Oncol. 3, 13 (2014).
2. Le Tourneau, C. et al. Molecularly targeted therapy based on tumour molecular profiling versus conventional therapy for advanced cancer (SHIVA): a multicentre, open-label, proof-of-concept, randomised, controlled phase 2 trial. Lancet Oncol. 16, 1324–1334 (2015).
3. von Hoff, D. D. et al. Pilot study using molecular profiling of patients' tumors to find potential targets and select treatments for their refractory cancers. J. Clin. Oncol. 28, 4877–4883 (2010).
4. Le Tourneau, C. et al. SHIVA: randomized phase II trial comparing molecularly targeted therapy based on tumor molecular profiling versus conventional therapy in patients with refractory cancer — PFS ratio from patients who crossed-over [abstract]. J. Clin. Oncol. 34, 2535 (2016).
5. Schwaederle, M. et al. Precision oncology: the UC San Diego Moores Cancer Center PREDICT experience. Mol. Cancer Ther. 15, 743–752 (2016).
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