Mismatch Repair system protein deficiency as a resistance factor for locally advanced rectal adenocarcinoma patients receiving neoadjuvant chemo-radiotherapy
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cancer Research,Oncology
Link
https://www.nature.com/articles/s41416-023-02444-2.pdf
Reference60 articles.
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3. Bosset JF, Calais G, Mineur L, Maingon P, Stojanovic-Rundic S, Bensadounet RJ, EORTC Radiation Oncology Group, et al. Fluorouracil-based adjuvant chemotherapy after preoperative chemoradiotherapy in rectal cancer: long-term results of the EORTC 22921 randomized study. Lancet Oncol. 2014;15:184–90. https://doi.org/10.1016/S1470-2045(13)70599-0.
4. Weiser MR. Total neoadjuvant therapy for locally advanced rectal cancer: PRODIGE 23 trial. Ann Surg Oncol. 2022;29:1493–5. https://doi.org/10.1245/s10434-021-11104-9.
5. Bahadoer RR, Dijkstra EA, van Etten B, Marijnen CAM, Putter H, Meershoek-Klein Kranenbarg E, et al. Short-course radiotherapy followed by chemotherapy before total mesorectal excision (TME) versus preoperative chemoradiotherapy, TME, and optional adjuvant chemotherapy in locally advanced rectal cancer (RAPIDO): a randomized, open-label, phase 3 trial. Lancet Oncol. 2021;22:29–42. https://doi.org/10.1016/S1470-2045(20)30555-6.
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1. Higher rate of pathologic complete response in patients with early-onset locally advanced rectal cancer;ESMO Gastrointestinal Oncology;2024-03
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