Depletion of L-asparagine supply and apoptosis of leukemia cells induced by human glycosylasparaginase
Author:
Publisher
Springer Science and Business Media LLC
Subject
Oncology,Cancer Research,Hematology
Link
http://www.nature.com/articles/leu2008387.pdf
Reference12 articles.
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2. Ollenschläger G, Roth E, Linkesch W, Jansen S, Simmel A, Mödder B . Asparaginase-induced derangements of glutamine metabolism: the pathogenetic basis for some drug-related side-effects. Eur J Clin Invest 1988; 18: 512–516.
3. Kaartinen V, Mononen T, Laatikainen R, Mononen I . Substrate specificity and reaction mechanism of human glycosylasparaginase. The N-glycosidic linkage of various glycoasparagines is cleaved through a reaction mechanism similar to L-asparaginase. J Biol Chem 1992; 267: 6855–6858.
4. Mononen I, Heisterkamp N, Dunder U, Romppanen EL, Noronkoski T, Kuronen I et al. Recombinant glycosylasparaginase and in vitro correction of aspartylglycosaminuria. FASEB J 1995; 9: 428–433.
5. Dunder U, Kaartinen V, Valtonen P, Väänänen E, Kosma V-M, Heisterkamp N et al. Enzyme replacement therapy in a mouse model of aspartylglucosaminuria. FASEB J 2000; 14: 361–367.
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