Sphingosine 1-phosphate and cancer
Author:
Publisher
Springer Science and Business Media LLC
Subject
General Earth and Planetary Sciences,General Environmental Science
Link
http://www.nature.com/articles/nrc2875.pdf
Reference201 articles.
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4. Hannun, Y. A. & Obeid, L. M. Principles of bioactive lipid signalling: lessons from sphingolipids. Nature Rev. Mol. Cell Biol. 9, 139–150 (2008).
5. Xia, P. et al. An oncogenic role of sphingosine kinase. Curr. Biol. 10, 1527–1530 (2000). This paper reports the first demonstration that SK1 increases V12 RAS-dependent transformation of NIH3T3 fibroblasts to form fibrosarcoma cells.
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