cGAS drives noncanonical-inflammasome activation in age-related macular degeneration
Author:
Publisher
Springer Science and Business Media LLC
Subject
General Biochemistry, Genetics and Molecular Biology,General Medicine
Link
http://www.nature.com/articles/nm.4450.pdf
Reference81 articles.
1. Wong, W.L. et al. Global prevalence of age-related macular degeneration and disease burden projection for 2020 and 2040: a systematic review and meta-analysis. Lancet Glob. Health 2, e106–e116 (2014).
2. Ambati, J., Ambati, B.K., Yoo, S.H., Ianchulev, S. & Adamis, A.P. Age-related macular degeneration: etiology, pathogenesis, and therapeutic strategies. Surv. Ophthalmol. 48, 257–293 (2003).
3. Ambati, J., Atkinson, J.P. & Gelfand, B.D. Immunology of age-related macular degeneration. Nat. Rev. Immunol. 13, 438–451 (2013).
4. Kaneko, H. et al. DICER1 deficit induces Alu RNA toxicity in age-related macular degeneration. Nature 471, 325–330 (2011).
5. Tarallo, V. et al. DICER1 loss and Alu RNA induce age-related macular degeneration via the NLRP3 inflammasome and MyD88. Cell 149, 847–859 (2012).
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