The UK Biobank resource with deep phenotyping and genomic data

Author:

Bycroft Clare,Freeman Colin,Petkova Desislava,Band Gavin,Elliott Lloyd T.,Sharp Kevin,Motyer Allan,Vukcevic Damjan,Delaneau Olivier,O’Connell Jared,Cortes Adrian,Welsh Samantha,Young Alan,Effingham Mark,McVean Gil,Leslie Stephen,Allen Naomi,Donnelly Peter,Marchini Jonathan

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Reference48 articles.

1. Plenge, R. M., Scolnick, E. M. & Altshuler, D. Validating therapeutic targets through human genetics. Nat. Rev. Drug Discov. 12, 581–594 (2013).

2. The UK Biobank. UK Biobank Axiom Array Content Summary http://www.ukbiobank.ac.uk/wp-content/uploads/2014/04/UK-Biobank-Axiom-Array-Content-Summary-2014.pdf (2014).

3. The UK Biobank. Genotyping and Quality Control of UK Biobank, a Large-Scale, Extensively Phenotyped Prospective Resource http://biobank.ctsu.ox.ac.uk/crystal/docs/genotyping_qc.pdf (2015).

4. Young, A. I., Wauthier, F. & Donnelly, P. Multiple novel gene-by-environment interactions modify the effect of FTO variants on body mass index. Nat. Commun. 7, 12724 (2016).

5. Astle, W. J. et al. The allelic landscape of human blood cell trait variation and links to common complex disease. Cell 167, 1415–1429.e19 (2016).

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