Streptococcal pyrogenic exotoxin B cleaves GSDMA and triggers pyroptosis
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
https://www.nature.com/articles/s41586-021-04384-4.pdf
Reference40 articles.
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3. Cole, J. N., Barnett, T. C., Nizet, V. & Walker, M. J. Molecular insight into invasive group A streptococcal disease. Nat. Rev. Microbiol. 9, 724–736 (2011).
4. Musser, J. M., Stockbauer, K., Kapur, V. & Rudgers, G. W. Substitution of cysteine 192 in a highly conserved Streptococcus pyogenes extracellular cysteine protease (interleukin 1beta convertase) alters proteolytic activity and ablates zymogen processing. Infect. Immun. 64, 1913–1917 (1996).
5. Svensson, M. D. et al. Role for a secreted cysteine proteinase in the establishment of host tissue tropism by group A streptococci. Mol. Microbiol. 38, 242–253 (2000).
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