The scaffold protein KSR1, a novel therapeutic target for the treatment of Merlin-deficient tumors
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cancer Research,Genetics,Molecular Biology
Link
http://www.nature.com/articles/onc2015404.pdf
Reference36 articles.
1. Hanemann CO . Magic but treatable? Tumours due to loss of Merlin. Brain 2008; 131: 606–615.
2. Evans DG . Neurofibromatosis type 2 (NF2): a clinical and molecular review. Orphanet J Rare Dis 2009; 4: 16.
3. Zhou L, Hanemann CO . Merlin, a multi-suppressor from cell membrane to the nucleus. FEBS Lett 2012; 586: 1403–1408.
4. Rong R, Tang X, Gutmann DH, Ye K . Neurofibromatosis 2 (NF2) tumor suppressor Merlin inhibits phosphatidylinositol 3-kinase through binding to PIKE-L. Proc Natl Acad Sci USA 2004; 101: 18200–18205.
5. Zhou L, Ercolano E, Ammoun S, Schmid MC, Barczyk MA, Hanemann CO . Merlin-deficient human tumors show loss of contact inhibition and activation of Wnt/beta-catenin signaling linked to the PDGFR/Src and Rac/PAK pathways. Neoplasia 2011; 13: 1101–1112.
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