Targeting of hepatic angiotensinogen using chemically modified siRNAs results in significant and sustained blood pressure lowering in a rat model of hypertension

Author:

Olearczyk Jeffrey,Gao Sheng,Eybye Marianne,Yendluri Satyasri,Andrews Lori,Bartz Steven,Cully Doris,Tadin-Strapps Marija

Publisher

Springer Science and Business Media LLC

Subject

Cardiology and Cardiovascular Medicine,Physiology,Internal Medicine

Reference55 articles.

1. Kearney PM, Whelton M, Reynolds K, Muntner P, Whelton PK, He J . Global burden of hypertension: analysis of worldwide data. Lancet 2005; 365: 217–223.

2. Atlas SA . The renin-angiotensin aldosterone system: pathophysiological role and pharmacologic inhibition. J Manag Care Pharm 2007; 13 (Suppl B): 9–20.

3. Corvol P, Soubrier F, Jeunemaitre X . Molecular genetics of the renin-angiotensin-aldosterone system in human hypertension. Pathol Biol (Paris) 1997; 45: 229–239.

4. Brasier AR, Li J . Mechanisms for inducible control of angiotensinogen gene transcription. Hypertension 1996; 27 (Pt 2): 465–475.

5. Morgan L, Broughton Pipkin F, Kalsheker N . Angiotensinogen: molecular biology, biochemistry and physiology. Int J Biochem Cell Biol 1996; 28: 1211–1222.

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