The prognostic impact of FLT3-ITD and NPM1 mutations in patients with relapsed acute myeloid leukemia and intermediate-risk cytogenetics-Reference-Cited by-同舟云学术

The prognostic impact of FLT3-ITD and NPM1 mutations in patients with relapsed acute myeloid leukemia and intermediate-risk cytogenetics

Published:2013-05 Issue:5 Volume:3 Page:e116-e116
ISSN:2044-5385
Container-title:Blood Cancer Journal
language:en
Short-container-title:Blood Cancer Journal

Author:

How J,Sykes J,Minden M D,Gupta V,Yee K W L,Schimmer A D,Schuh A C,Kamel-Reid S,Brandwein J M

Publisher

Springer Science and Business Media LLC

Subject

Oncology,Hematology

Link

http://www.nature.com/articles/bcj201314.pdf

Reference20 articles.

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2. Fröhling S, Schlenk RF, Breitruck J, Benner A, Kreitmeier S, Tobis K et al. Prognostic significance of activating FLT3 mutations in younger adults (16 to 60 years) with acute myeloid leukemia and normal cytogenetics: a study of the AML Study Group Uhn. Blood 2002; 100: 4372–4380.

3. Schnittger S, Schoch C, Kern W, Mecucci C, Tschulik C, Martelli C . Nucleophosmin gene mutations are predictors of favorable prognosis in acute myelogenous leukemia with a normal karyotype. Blood 2005; 106: 3733–3739.

4. Verhaak RGW, Goudswaard CS, van Putten W, Bijl MA, Sanders MA, Hugens W et al. Mutations in nucleophosmin (NPM1) in acute myeloid leukemia (AML): association with other gene abnormalities and previously established gene expression signatures and their favorable prognostic significance. Blood 2005; 106: 3747–3754.

5. Palmisano M, Grafone T, Ottaviani E, Testoni N, Baccarani M, Martinelli G et al. NPM1 mutations are more stable than FLT3 mutations during the course of disease in patients with acute myeloid leukaemia. Haematologica 2007; 92: 1268–1269.

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