A detergent-based assay for the detection of promiscuous inhibitors
Author:
Publisher
Springer Science and Business Media LLC
Subject
General Biochemistry, Genetics and Molecular Biology
Link
http://www.nature.com/articles/nprot.2006.77.pdf
Reference13 articles.
1. Hajduk, P.J., Huth, J.R. & Fesik, S.W. Druggability indices for protein targets derived from NMR-based screening data. J. Med. Chem. 48, 2518–2525 (2005).
2. Rishton, G.M. Reactive compounds and in vitro false positives in HTS. Drug Discov. Today 2, 382–384 (1997).
3. Walters, W.P. & Namchuk, M. Designing screens: how to make your hits a hit. Nat. Rev. Drug Discov. 2, 259–266 (2003).
4. Feng, B. & Shoichet, B.K. Synergy and antagonism of promiscuous inhibition in multiple-compound mixtures. J. Med. Chem. 49, 2151–2154 (2006).
5. Feng, B.Y. et al. High-throughput assays for promiscuous inhibitors. Nat. Chem. Biol. 1, 146–148 (2005).
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