Cannabidiol is a partial agonist at dopamine D2High receptors, predicting its antipsychotic clinical dose
Author:
Publisher
Springer Science and Business Media LLC
Subject
Biological Psychiatry,Cellular and Molecular Neuroscience,Psychiatry and Mental health
Link
http://www.nature.com/articles/tp2016195.pdf
Reference30 articles.
1. Miyamoto S, Miyake N, Jarskog LF, Fleischhacker WW, Lieberman JA . Pharmacological treatment of schizophrenia: a critical review of the pharmacology and clinical effects of current and future therapeutic agents. Mol Psychiatry 2012; 17: 1206–1227.
2. Leweke FM, Piomelli D, Pahlisch F, Muhl D, Gerth CW, Hoyer C et al. Cannabidiol enhances anandamide signaling and alleviates psychotic symptoms of schizophrenia. Transl Psychiatry 2012; 2: e94.
3. Davenport L Cannabis compound may augment antipsychotic meds. Available at www.medscape.com/viewarticle/862312 (accessed on 9 May 2016).
4. Seeman P, Chau-Wong M, Tedesco J, Wong K . Brain receptors for antipsychotic drugs and dopamine: Direct binding assays. Proc Natl Acad Sci USA 1975; 72: 4376–4380.
5. Seeman P . All roads to schizophrenia lead to dopamine supersensitivity and elevated dopamine D2High receptors. CNS Neurosci Ther 2011; 17: 118–132.
Cited by 130 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. Effects of Cannabidiol on Bone Quality in Ovariectomized Rats;Calcified Tissue International;2024-09-09
2. Investigating Cannabidiol's potential as a supplementary treatment for schizophrenia: A narrative review;European Journal of Pharmacology;2024-09
3. Cannabidiol Increases Psychotropic Effects and Plasma Concentrations of Δ9‐Tetrahydrocannabinol Without Improving Its Analgesic Properties;Clinical Pharmacology & Therapeutics;2024-07-25
4. Natural Product-Inspired Dopamine Receptor Ligands;Journal of Medicinal Chemistry;2024-07-22
5. CBD Versus CBDP: Comparing In Vitro Receptor-Binding Activities;International Journal of Molecular Sciences;2024-07-15
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3