Targeting the protein kinase C family: are we there yet?

Author:

Mackay Helen J.,Twelves Christopher J.

Publisher

Springer Science and Business Media LLC

Subject

General Earth and Planetary Sciences,General Environmental Science

Reference132 articles.

1. Fields, A. P. & Gustafson, W. C. in Methods in Molecular Biology (ed. Newton, A. C.) 519–537 (Humana Press Inc., Totowa, New Jersey, 2003).

2. Blobe, G. C., Obeid, L. M. & Hannun, Y. A. Regulation of protein kinase C and role in cancer biology. Cancer Met. Rev. 13, 724–730 (1994).

3. Castagna, M. et al. Direct activation of calcium-activated, phopholipid-dependent protein kinase by tumour-promoting phorbol esters. J. Biol. Chem. 257, 7847–7851 (1982).

4. Mackay, H. & Twelves, C. J. Protein kinase C: a target for anticancer drugs? Endocrine Relat. Cancer 10, 386–396 (2003).

5. Takai, Y. et al. Calcium-dependent activation of a multi-functional protein kinase by membrane phospholipids. J. Biol. Chem. 3692–3695 (1979).

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