Safeguarding mitochondrial genomes in higher eukaryotes
Author:
Publisher
Springer Science and Business Media LLC
Subject
Molecular Biology,Structural Biology
Link
https://www.nature.com/articles/s41594-020-0474-9.pdf
Reference96 articles.
1. Sagan, L. On the origin of mitosing cells. J. Theor. Biol. 14, 255–574 (1967).
2. Falkenberg, M. Mitochondrial DNA replication in mammalian cells: overview of the pathway. Essays Biochem. 62, 287–296 (2018).
3. Kukat, C. et al. Cross-strand binding of TFAM to a single mtDNA molecule forms the mitochondrial nucleoid. Proc. Natl Acad. Sci. USA 112, 11288–11293 (2015).
4. Kukat, C. et al. Super-resolution microscopy reveals that mammalian mitochondrial nucleoids have a uniform size and frequently contain a single copy of mtDNA. Proc. Natl Acad. Sci. USA 108, 13534–13539 (2011). Super-resolution imaging reveals that nucleoids in mammalian mitochondria display uniform size, and each contains a single copy of mtDNA. In addition, replication occurs only in a subset of nucleoids.
5. Larsson, N.-G. et al. Mitochondrial transcription factor A is necessary for mtDNA maintenance and embryogenesis in mice. Nat. Genet. 18, 231–236 (1998).
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