A look into the dynamic process of proofreading in DNA polymerase-γ at near-atomic resolution
Author:
Publisher
Springer Science and Business Media LLC
Subject
Molecular Biology,Structural Biology
Link
https://www.nature.com/articles/s41594-023-01001-y.pdf
Reference4 articles.
1. Taylor, R. W. & Turnbull, D. M. Mitochondrial DNA mutations in human disease. Nat. Rev. Genet. 6, 389–402 (2005). A review article that summerizes mitochondrial DNA mutations implicated in diseases.
2. Szczepanowska, K. & Trifunovic, A. Different faces of mitochondrial DNA mutators. Biochim. Biophys. Acta 1847, 1362–1372 (2015). A review article that presents that reduced Polγ replication fidelity can accelerate the aging process.
3. Young, M. J. Off-target effects of drugs that disrupt human mitochondrial DNA maintenance. Front. Mol. Biosci. 4, 74 (2017). A review article that discusses the mitochondrial toxicity of antiviral reagents.
4. Kunkel, T. A. & Alexander, P. S. The base substitution fidelity of eucaryotic DNA polymerases. Mispairing frequencies, site preferences, insertion preferences, and base substitution by dislocation. J. Biol. Chem. 261, 160–166 (1986). A research article that examined mismatch frequency and first reported on G·T base pairs as the most common mistake made by DNA polymerases.
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