Dimers of DNA-PK create a stage for DNA double-strand break repair-Reference-Cited by-同舟云学术

Dimers of DNA-PK create a stage for DNA double-strand break repair

Published:2020-10-19 Issue:1 Volume:28 Page:13-19
ISSN:1545-9993
Container-title:Nature Structural & Molecular Biology
language:en
Short-container-title:Nat Struct Mol Biol

Author:

Chaplin Amanda K.,Hardwick Steven W.,Liang Shikang,Kefala Stavridi Antonia,Hnizda Ales,Cooper Lee R.,De Oliveira Taiana Maia,Chirgadze Dimitri Y.,Blundell Tom L.^ORCID

Publisher

Springer Science and Business Media LLC

Subject

Molecular Biology,Structural Biology

Link

https://www.nature.com/articles/s41594-020-00517-x.pdf

Reference39 articles.

1. Chirgadze, D. Y., Ascher, D. B., Blundell, T. L. & Sibanda, B. L. DNA-PKcs, allostery and DNA double-strand break repair: defining the structure and setting the stage. Methods Enzymol. 592, 145–157 (2017).

2. Liang, S. et al. Achieving selectivity in space and time with DNA double-strand-break response and repair: molecular stages and scaffolds come with strings attached. Stuct. Chem. 28, 161–171 (2017).

3. Walker, J. R., Corpina, R. A. & Goldberg, J. Structure of the Ku heterodimer bound to DNA and its implications for double-strand break repair. Nature 412, 607–614 (2001).

4. Gell, D. & Jackson, S. P. Mapping of protein–protein interactions within the DNA-dependent protein kinase complex. Nucleic Acids Res. 27, 3494–3502 (1999).

5. Singleton, B. K., Torres-Arzayus, M. I., Rottinghaus, S. T., Taccioli, G. E. & Jeggo, P. A. The C terminus of Ku80 activates the DNA-dependent protein kinase catalytic subunit. Mol. Cell. Biol. 19, 3267–3277 (1999).

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