Polygenic adaptation: a unifying framework to understand positive selection
Author:
Publisher
Springer Science and Business Media LLC
Subject
Genetics (clinical),Genetics,Molecular Biology
Link
http://www.nature.com/articles/s41576-020-0250-z.pdf
Reference145 articles.
1. Pritchard, J. K. & Di Rienzo, A. Adaptation — not by sweeps alone. Nat. Rev. Genet. 11, 665–667 (2010).
2. Pritchard, J. K., Pickrell, J. K. & Coop, G. The genetics of human adaptation: hard sweeps, soft sweeps, and polygenic adaptation. Curr. Biol. 20, R208–R215 (2010). This key paper defines the concept of polygenic adaptation.
3. Boyle, E. A., Li, Y. I. & Pritchard, J. K. An expanded view of complex traits: from polygenic to omnigenic. Cell 169, 1177–1186 (2017). This landmark paper introduces the omnigenic model and links quantitative genetics with molecular biology.
4. Csillery, K., Rodriguez-Verdugo, A., Rellstab, C. & Guillaume, F. Detecting the genomic signal of polygenic adaptation and the role of epistasis in evolution. Mol. Ecol. 27, 606–612 (2018).
5. Stephan, W. Selective sweeps. Genetics 211, 5–13 (2019).
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