Integration of chemical-genetic and genetic interaction data links bioactive compounds to cellular target pathways-Reference-Cited by-同舟云学术

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Integration of chemical-genetic and genetic interaction data links bioactive compounds to cellular target pathways

Published:2003-12-07 Issue:1 Volume:22 Page:62-69
ISSN:1087-0156
Container-title:Nature Biotechnology
language:en
Short-container-title:Nat Biotechnol

Author:

Parsons Ainslie B,Brost Renée L,Ding Huiming,Li Zhijian,Zhang Chaoying,Sheikh Bilal,Brown Grant W,Kane Patricia M,Hughes Timothy R,Boone Charles

Publisher

Springer Science and Business Media LLC

Subject

Biomedical Engineering,Molecular Medicine,Applied Microbiology and Biotechnology,Bioengineering,Biotechnology

Link

http://www.nature.com/articles/nbt919.pdf

Reference42 articles.

1. Winzeler, E.A. et al. Functional characterization of the S. cerevisiae genome by gene deletion and parallel analysis. Science 285, 901–906 (1999).

2. Hughes, T.R. et al. Functional discovery via a compendium of expression profiles. Cell 102, 109–926 (2000).

3. Marton, M.J. et al. Drug target validation and identification of secondary drug target effects using DNA microarrays. Nat. Med. 4, 1293–1301 (1998).

4. Hartwell, L.H., Szankasi, P., Roberts, C.J., Murray, A.W. & Friend, S.H. Integrating genetic approaches into the discovery of anticancer drugs. Science 278, 1064–1068 (1997).

5. Tong, A.H. et al. Systematic genetic analysis with ordered arrays of yeast deletion mutants. Science 294, 2364–2368 (2001).

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