Multi-omics dataset of bovine mammary epithelial cells stimulated by ten different essential amino acids-Reference-Cited by-同舟云学术

Multi-omics dataset of bovine mammary epithelial cells stimulated by ten different essential amino acids

Published:2024-03-12 Issue:1 Volume:11 Page:
ISSN:2052-4463
Container-title:Scientific Data
language:en
Short-container-title:Sci Data

Author:

Xu Lianbin,Wang Xiaowen,Li Xiuli,Liu Huawei,Zhao Jinshan,Bu Dengpan

Abstract

AbstractApplication of high-throughput sequencing and screening help to detect the transcriptional and metabolic discrepancies in organs provided with various levels of nutrients. The influences of individual essential amino acid (EAA) administration on transcriptomic and metabolomic profilings of bovine mammary epithelial cells (BMECs) were systematically investigated. A RNA sequencing and liquid chromatography-tandem mass spectrometry generated a comprehensive comparison of transcriptomics, non-targeted metabolomics and targeted amino acids profilings of BMECs with individual EAA stimulation by turn. The sequencing data and raw LC-MS/MS data of samples were presented in the databases of Gene Expression Omnibus, MetaboLights and Figshare for efficient reuse, including exploring the divergences in metabolisms between different EAAs and screening valuable genes and metabolites regulating casein synthesis.

Funder

Research Fund of Qingdao Special Food Research Institute

National Natural Science Foundation of China

Publisher

Springer Science and Business Media LLC

Link

https://www.nature.com/articles/s41597-024-03123-4.pdf

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