The role of double-strand break repair — insights from human genetics
Author:
Publisher
Springer Science and Business Media LLC
Subject
Genetics (clinical),Genetics,Molecular Biology
Link
http://www.nature.com/articles/nrg1746.pdf
Reference114 articles.
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3. d'Adda di Fagagna, F. et al. A DNA damage checkpoint response in telomere-initiated senescence. Nature 426, 194–198 (2003). This study shows that uncapped telomeres trigger activation of the DNA-damage-response pathway, which leads to senescence that is caused by cell-cycle-checkpoint arrest.
4. d'Adda di Fagagna, F., Teo, S. H. & Jackson, S. P. Functional links between telomeres and proteins of the DNA-damage response. Genes Dev. 18, 1781–1799 (2004).
5. Jackson, S. Sensing and repairing DNA double strand breaks. Carcinogenesis 23, 687–696 (2002).
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