The protective effect of cardiac gene transfer of CuZn–sod in comparison with the cardioprotector monohydroxyethylrutoside against doxorubicin-induced cardiotoxicity in cultured cells

Author:

Abou El Hassan M A I,Heijn M,Rabelink M J W E,van der Vijgh W J F,Bast A,Hoeben R C

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Molecular Biology,Molecular Medicine

Reference37 articles.

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2. Goeptar AR, Groot EJ, Scheerens H, et al. Cytotoxicity of mitomycin C and adriamycin in freshly isolated rat hepatocytes: the role of cytochrome P450. Cancer Res. 1994;54:2411–2418.

3. Minotti G . Adriamycin-dependent release of iron from microsomal membranes. Arch Biochem Biophys. 1989;268:398–403.

4. Van Acker SABE, Boven E, Kuiper K, et al. Monohyroxyethylrutoside, a dose dependent cardioprotective agent, does not affect the antitumor activity of doxorubicin. Clin Cancer Res. 1997;3:1747–1754.

5. Van Acker FAA, Van Acker SABE, Kramer K, et al. MonoHER protects against chronic doxorubicin-induced cardiotoxicity when administered only once per week. Clin Cancer Res. 2000;6(4):1337–1341.

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