Tumor-selective drug activation: a GDEPT approach utilizing cytochrome P450 1A1 and AQ4N-Reference-Cited by-同舟云学术

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Tumor-selective drug activation: a GDEPT approach utilizing cytochrome P450 1A1 and AQ4N

Published:2006-01-06 Issue:6 Volume:13 Page:598-605
ISSN:0929-1903
Container-title:Cancer Gene Therapy
language:en
Short-container-title:Cancer Gene Ther

Author:

Yakkundi A,McErlane V,Murray M,McCarthy H O,Ward C,Hughes C M,Patterson L H,Hirst D G,McKeown S R,Robson T

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Molecular Biology,Molecular Medicine

Link

http://www.nature.com/articles/7700933.pdf

Reference35 articles.

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2. Vaupel P, Harrison L . Tumor hypoxia: causative factors, compensatory mechanisms, and cellular response. Oncologist 2004; 9(Suppl 5): 4–9. 9/suppl_5/4 [pii]; 10.1634/theoncologist.9-90005-4 [doi].

3. Gandara DR, Lara Jr PN, Goldberg Z, Le QT, Mack PC, Lau DH et al. Tirapazamine: prototype for a novel class of therapeutic agents targeting tumor hypoxia. Semin Oncol 2002; 29: 102–109. asonc02901e0102 [pii].

4. Brown JM, Siim BG . Hypoxia-specific cytotoxins in Cancer Therapy. Semin Radiat Oncol 1996; 6: 22–36. 10.1053/SRAO0060022 [doi]; 00600022 [pii].

5. Stratford IJ, Williams KJ, Cowen RL, Jaffar M . Combining bioreductive drugs and radiation for the treatment of solid tumors. Semin Radiat Oncol 2003; 13: 42–52. 10.1053/srao.2003.50008 [doi]; S1053429603500078 [pii].

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