Reduced-toxicity myeloablative conditioning regimen using fludarabine and full doses of intravenous busulfan in pediatric patients not eligible for standard myeloablative conditioning regimens: Results of a multicenter prospective phase 2 trial

Author:

Rialland FannyORCID,Grain Audrey,Labopin MyriamORCID,Michel GerardORCID,Gandemer Virginie,Paillard Catherine,Pochon Cécile,Clement Laurence,Brissot Eolia,Jubert Charlotte,Sirvent Anne,Rohrlich Pierre SimonORCID,Plantaz Dominique,Dalle Jean-Hugues,Mohty MohamadORCID

Publisher

Springer Science and Business Media LLC

Subject

Transplantation,Hematology

Reference21 articles.

1. Mohty M, Labopin M, Volin L, Gratwohl A, Socié G, Esteve J, et al. Reduced-intensity versus conventional myeloablative conditioning allogeneic stem cell transplantation for patients with acute lymphoblastic leukemia: A retrospective study from the European Group for blood and marrow transplantation. Blood. 2010;116:4439–43. https://doi.org/10.1182/blood-2010-02-266551

2. Pulsipher MA, Levine JE, Hayashi RJ, Chan KW, Anderson P, Osunkwo I, et al. Safety and efficacy of allogeneic PBSC collection in normal pediatric donors: The pediatric blood and marrow transplant consortium experience (PBMTC) 1996-2003. Bone Marrow Transpl. 2005;35:361–7. https://doi.org/10.1038/sj.bmt.1704743

3. Pulsipher MA, Nagler A, Iannone R, Nelson RM. Weighing the risks of G-CSF administration, leukopheresis, and standard marrow harvest: Ethical and safety considerations for normal pediatric hematopoietic cell donors. Pediatr Blood Cancer. 2006;46:422–33. https://doi.org/10.1002/pbc.20708

4. Pulsipher MA, Boucher KM, Wall D, Frangoul H, Duval M, Goyal RK, et al. Reduced-intensity allogeneic transplantation in pediatric patients ineligible for myeloablative therapy: results of the Pediatric Blood and Marrow Transplant Consortium Study ONC0313. Blood. 2009;114:1429–36. https://doi.org/10.1182/blood-2009-01-196303

5. Satwani P, Cooper N, Rao K, Veys P, Amrolia P. Reduced intensity conditioning and allogeneic stem cell transplantation in childhood malignant and nonmalignant diseases. Bone Marrow Transpl. 2008;41:173–82. https://doi.org/10.1038/sj.bmt.1705923

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