Cytomegalovirus (CMV)-specific cytotoxic T lymphocyte therapy resolve CMV diseases and refractory CMV infections in paediatric recipients of allogeneic haematopoietic stem cell transplantation

Author:

Wang Xiaodong,Yu UetORCID,Yang Chunlan,Wang Chunjing,Zhang Xiaoling,Li Yue,Li Changgang,Wen Feiqiu,Liu Sixi

Publisher

Springer Science and Business Media LLC

Subject

Transplantation,Hematology

Reference12 articles.

1. Feuchtinger T, Opherk K, Bethge WA, Topp MS, Schuster FR, Weissinger EM, et al. Adoptive transfer of pp65-specific T cells for the treatment of chemorefractory cytomegalovirus disease or reactivation after haploidentical and matched unrelated stem cell transplantation. Blood. 2010;116:4360–7. https://doi.org/10.1182/blood-2010-01-262089. e-pub ahead of print 2010/07/14.

2. Zhao XY, Pei XY, Chang YJ, Yu XX, Xu LP, Wang Y, et al. First-line therapy with donor-derived human cytomegalovirus (HCMV)-specific T cells reduces persistent HCMV infection by promoting antiviral immunity after allogenic stem cell transplantation. Clin Infect Dis. 2020;70:1429–37. https://doi.org/10.1093/cid/ciz368. e-pub ahead of print 2019/05/09.

3. Ljungman P, de la Camara R, Robin C, Crocchiolo R, Einsele H, Hill JA, et al. Guidelines for the management of cytomegalovirus infection in patients with haematological malignancies and after stem cell transplantation from the 2017 European Conference on Infections in Leukaemia (ECIL 7). Lancet Infect Dis. 2019;19:e260–e272. https://doi.org/10.1016/s1473-3099(19)30107-0. e-pub ahead of print 2019/06/04.

4. Pfirrmann V, Oelsner S, Rettinger E, Huenecke S, Bonig H, Merker M, et al. Cytomegalovirus-specific cytokine-induced killer cells: concurrent targeting of leukemia and cytomegalovirus. Cytotherapy. 2015;17:1139–51. https://doi.org/10.1016/j.jcyt.2015.04.011. e-pub ahead of print 2015/06/15.

5. Gupta MP, Koenig LR, Doubrovina E, Hasan A, Dahi PB, O’Reilly RJ, et al. Ocular outcomes after treatment of cytomegalovirus (CMV) retinitis using adoptive immunotherapy with CMV-specific cytotoxic T-lymphocytes. Ophthalmol Retina. 2021. https://doi.org/10.1016/j.oret.2021.04.009. e-pub ahead of print 2021/04/24.

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