Associations of human leukocyte antigens with autoimmune diseases: challenges in identifying the mechanism
Author:
Publisher
Springer Science and Business Media LLC
Subject
Genetics(clinical),Genetics
Link
http://www.nature.com/articles/jhg2015100.pdf
Reference77 articles.
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3. Gregersen, P. K., Silver, J. & Winchester, R. J. The shared epitope hypothesis. An approach to understanding the molecular genetics of susceptibility to rheumatoid arthritis. Arthritis Rheum. 30, 1205–1213 (1987).
4. Mackie, S. L., Taylor, J. C., Martin, S. G ., Consortium, Y., Consortium, U. Wordsworth, P. et al. A spectrum of susceptibility to rheumatoid arthritis within HLA-DRB1: stratification by autoantibody status in a large UK population. Genes Immun. 13, 120–128 (2012).
5. Morgan, A. W., Thomson, W., Martin, S. G . Yorkshire Early Arthritis Register, C., Carter, A. M ., Consortium, U. K. R. A. G. et al. Reevaluation of the interaction between HLA-DRB1 shared epitope alleles, PTPN22, and smoking in determining susceptibility to autoantibody-positive and autoantibody-negative rheumatoid arthritis in a large UK Caucasian population. Arthritis Rheum. 60, 2565–2576 (2009).
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