An altered intestinal mucosal microbiome in HIV-1 infection is associated with mucosal and systemic immune activation and endotoxemia-Reference-Cited by-同舟云学术

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An altered intestinal mucosal microbiome in HIV-1 infection is associated with mucosal and systemic immune activation and endotoxemia

Published:2014-01-08 Issue:4 Volume:7 Page:983-994
ISSN:1933-0219
Container-title:Mucosal Immunology
language:en
Short-container-title:Mucosal Immunol

Author:

Dillon S M,Lee E J,Kotter C V,Austin G L,Dong Z,Hecht D K,Gianella S,Siewe B,Smith D M,Landay A L,Robertson C E,Frank D N,Wilson C C

Publisher

Springer Science and Business Media LLC

Subject

Immunology,Immunology and Allergy

Link

http://www.nature.com/articles/mi2013116.pdf

Reference48 articles.

1. Kotler, D.P., Gaetz, H.P., Lange, M., Klein, E.B. & Holt, P.R. Enteropathy associated with the acquired immunodeficiency syndrome. Ann. Intern. Med. 101, 421–428 (1984).

2. Epple, H.J. et al. Acute HIV infection induces mucosal infiltration with CD4+ and CD8+ T cells, epithelial apoptosis, and a mucosal barrier defect. Gastroenterology 139, 1289–1300 (2010).

3. Sankaran, S. et al. Rapid onset of intestinal epithelial barrier dysfunction in primary human immunodeficiency virus infection is driven by an imbalance between immune response and mucosal repair and regeneration. J. Virol. 82, 538–545 (2008).

4. Brenchley, J.M. et al. CD4+ T cell depletion during all stages of HIV disease occurs predominantly in the gastrointestinal tract. J. Exp. Med. 200, 749–759 (2004).

5. Brenchley, J.M. et al. Differential Th17 CD4 T-cell depletion in pathogenic and nonpathogenic lentiviral infections. Blood 112, 2826–2835 (2008).

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