CRISPR–Cas9-mediated base-editing screening in mice identifies DND1 amino acids that are critical for primordial germ cell development
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cell Biology
Link
http://www.nature.com/articles/s41556-018-0202-4.pdf
Reference40 articles.
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2. Doudna, J. A. & Charpentier, E. Genome editing. The new frontier of genome engineering with CRISPR–Cas9. Science 346, 1258096 (2014).
3. Zhang, X., Wang, L., Liu, M. & Li, D. CRISPR/Cas9 system: a powerful technology for in vivo and ex vivo gene therapy. Sci. China Life Sci. 60, 468–475 (2017).
4. Wu, Y. et al. Correction of a genetic disease by CRISPR–Cas9-mediated gene editing in mouse spermatogonial stem cells. Cell Res. 25, 67–79 (2015).
5. Komor, A. C., Kim, Y. B., Packer, M. S., Zuris, J. A. & Liu, D. R. Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage. Nature 533, 420–424 (2016).
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