Structure and inhibition mechanism of the catalytic domain of human squalene epoxidase-Reference-Cited by-同舟云学术

Structure and inhibition mechanism of the catalytic domain of human squalene epoxidase

Published:2019-01-09 Issue:1 Volume:10 Page:
ISSN:2041-1723
Container-title:Nature Communications
language:en
Short-container-title:Nat Commun

Author:

Padyana Anil K.^ORCID,Gross Stefan^ORCID,Jin Lei,Cianchetta Giovanni,Narayanaswamy Rohini,Wang Feng,Wang Rui,Fang Cheng,Lv Xiaobing,Biller Scott A.,Dang Lenny,Mahoney Christopher E.^ORCID,Nagaraja Nelamangala,Pirman David,Sui Zhihua,Popovici-Muller Janeta,Smolen Gromoslaw A.^ORCID

Publisher

Springer Science and Business Media LLC

Subject

General Physics and Astronomy,General Biochemistry, Genetics and Molecular Biology,General Chemistry

Link

http://www.nature.com/articles/s41467-018-07928-x.pdf

Reference40 articles.

1. Goldstein, J. L. & Brown, M. S. A century of cholesterol and coronaries: from plaques to genes to statins. Cell 161, 161–172 (2015).

2. Tomkin, G. H. & Owens, D. Investigational therapies for hypercholesterolemia. Expert. Opin. Investig. Drugs 26, 603–617 (2017).

3. Clendening, J. W. & Penn, L. Z. Targeting tumor cell metabolism with statins. Oncogene 31, 4967–4978 (2012).

4. Mahoney, C. E. et al. A chemical biology screen identifies a unique vulnerability of neuroendocrine cancer cells to SQLE inhibition. Nat. Commun. https://doi.org/10.1038/s41467-018-07959-4 (2018).

5. Leichner, G. S., Avner, R., Harats, D. & Roitelman, J. Metabolically regulated endoplasmic reticulum-associated degradation of 3-hydroxy-3-methylglutaryl-CoA reductase: evidence for requirement of a geranylgeranylated protein. J. Biol. Chem. 286, 32150–32161 (2011).

Cited by 91 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Structural and Functional Characterization of a Novel Class A Flavin Monooxygenase from Bacillus niacini;Biochemistry;2024-09-12

2. Clinical Course, Antifungal Susceptibility, and Genomic Sequencing of Trichophyton indotineae;JAMA Dermatology;2024-07-01

3. A review on potential therapeutic targets for the treatment of leishmaniasis;Parasitology International;2024-06

4. Targeting squalene epoxidase restores anti-PD-1 efficacy in metabolic dysfunction-associated steatohepatitis-induced hepatocellular carcinoma;Gut;2024-05-13

5. Depletion of squalene epoxidase in synergy with glutathione peroxidase 4 inhibitor RSL3 overcomes oxidative stress resistance in lung squamous cell carcinoma;Precision Clinical Medicine;2024-05-01