Late-life targeting of the IGF-1 receptor improves healthspan and lifespan in female mice-Reference-Cited by-同舟云学术

Late-life targeting of the IGF-1 receptor improves healthspan and lifespan in female mice

Published:2018-06-19 Issue:1 Volume:9 Page:
ISSN:2041-1723
Container-title:Nature Communications
language:en
Short-container-title:Nat Commun

Author:

Mao Kai,Quipildor Gabriela Farias,Tabrizian Tahmineh,Novaj Ardijana^ORCID,Guan Fangxia,Walters Ryan O.,Delahaye Fabien,Hubbard Gene B.,Ikeno Yuji,Ejima Keisuke^ORCID,Li Peng^ORCID,Allison David B.,Salimi-Moosavi Hossein,Beltran Pedro J.,Cohen Pinchas,Barzilai Nir,Huffman Derek M.

Publisher

Springer Science and Business Media LLC

Subject

General Physics and Astronomy,General Biochemistry, Genetics and Molecular Biology,General Chemistry

Link

http://www.nature.com/articles/s41467-018-04805-5.pdf

Reference53 articles.

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3. Clancy, D. J. et al. Extension of life-span by loss of CHICO, a Drosophila insulin receptor substrate protein. Science 292, 104–106 (2001).

4. Bartke, A., List, E. O. & Kopchick, J. J. The somatotropic axis and aging: benefits of endocrine defects. Growth Horm. IGF Res. 27, 41–45 (2016).

5. Barzilai, N. & Ferrucci, L. Insulin resistance and aging: a cause or a protective response? J. Gerontol. A Biol. Sci. Med. Sci. 67, 1329–1331 (2012).

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