Abstract
AbstractBiological tissues, such as muscle, can increase their mechanical strength after swelling due to the existence of many biological membrane barriers that can regulate the transmembrane transport of water molecules and ions. Oppositely, typical synthetic materials show a swelling-weakening behavior, which always suffers from a sharp decline in mechanical strength after swelling, because of the dilution of the network. Here, we describe a swelling-strengthening phenomenon of polymer materials achieved by a bioinspired strategy. Liposomal membrane nanobarriers are covalently embedded in a crosslinked network to regulate transmembrane transport. After swelling, the stretched network deforms the liposomes and subsequently initiates the transmembrane diffusion of the encapsulated molecules that can trigger the formation of a new network from the preloaded precursor. Thanks to the tough nature of the double-network structure, the swelling-strengthening phenomenon is achieved to polymer hydrogels successfully. Swelling-triggered self-strengthening enables the development of various dynamic materials.
Funder
National Natural Science Foundation of China
Publisher
Springer Science and Business Media LLC
Subject
General Physics and Astronomy,General Biochemistry, Genetics and Molecular Biology,General Chemistry
Reference47 articles.
1. van Oosten, A. S. G. et al. Emergence of tissue-like mechanics from fibrous networks confined by close-packed cells. Nature 573, 96–101 (2019).
2. Wang, N., Butler, J. P. & Ingber, D. E. Mechanotransduction across the cell surface and through the cytoskeleton. Science 260, 1124–1127 (1993).
3. Fung, Y. C. Biomechanics: Mechanical Properties of Living Tissues (Spinger Science & Business Media, 2013).
4. Burdick, J. A. & Murphy, W. L. Moving from static to dynamic complexity in hydrogel design. Nat. Commun. 3, 1269 (2012).
5. Jatav, V. S., Singh, H. & Singh, S. K. Recent trends on hydrogel in human body. Int. J. Res. Pharm. Biomed. Sci. 2, 442–447 (2011).
Cited by
74 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献