Genome-wide association study in 79,366 European-ancestry individuals informs the genetic architecture of 25-hydroxyvitamin D levels
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Published:2018-01-17
Issue:1
Volume:9
Page:
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ISSN:2041-1723
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Container-title:Nature Communications
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language:en
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Short-container-title:Nat Commun
Author:
Jiang Xia, O’Reilly Paul F., Aschard HuguesORCID, Hsu Yi-Hsiang, Richards J. BrentORCID, Dupuis Josée, Ingelsson Erik, Karasik David, Pilz Stefan, Berry Diane, Kestenbaum Bryan, Zheng Jusheng, Luan Jianan, Sofianopoulou Eleni, Streeten Elizabeth A., Albanes Demetrius, Lutsey Pamela L., Yao Lu, Tang Weihong, Econs Michael J., Wallaschofski Henri, Völzke Henry, Zhou Ang, Power Chris, McCarthy Mark I.ORCID, Michos Erin D., Boerwinkle Eric, Weinstein Stephanie J., Freedman Neal D., Huang Wen-Yi, Van Schoor Natasja M., van der Velde Nathalie, Groot Lisette C. P. G. M. deORCID, Enneman Anke, Cupples L. Adrienne, Booth Sarah L., Vasan Ramachandran S., Liu Ching-TiORCID, Zhou Yanhua, Ripatti Samuli, Ohlsson Claes, Vandenput Liesbeth, Lorentzon Mattias, Eriksson Johan G., Shea M. Kyla, Houston Denise K., Kritchevsky Stephen B., Liu Yongmei, Lohman Kurt K., Ferrucci Luigi, Peacock Munro, Gieger Christian, Beekman MarianORCID, Slagboom Eline, Deelen JorisORCID, Heemst Diana van, Kleber Marcus E.ORCID, März Winfried, de Boer Ian H., Wood Alexis C., Rotter Jerome I., Rich Stephen S., Robinson-Cohen Cassianne, den Heijer Martin, Jarvelin Marjo-Riitta, Cavadino Alana, Joshi Peter K.ORCID, Wilson James F.ORCID, Hayward CarolineORCID, Lind Lars, Michaëlsson Karl, Trompet Stella, Zillikens M. Carola, Uitterlinden Andre G., Rivadeneira FernandoORCID, Broer Linda, Zgaga Lina, Campbell Harry, Theodoratou Evropi, Farrington Susan M.ORCID, Timofeeva Maria, Dunlop Malcolm G., Valdes Ana M., Tikkanen Emmi, Lehtimäki Terho, Lyytikäinen Leo-PekkaORCID, Kähönen Mika, Raitakari Olli T., Mikkilä Vera, Ikram M. ArfanORCID, Sattar Naveed, Jukema J. WouterORCID, Wareham Nicholas J., Langenberg Claudia, Forouhi Nita G., Gundersen Thomas E., Khaw Kay-Tee, Butterworth Adam S., Danesh John, Spector Timothy, Wang Thomas J., Hyppönen Elina, Kraft Peter, Kiel Douglas P.
Publisher
Springer Science and Business Media LLC
Subject
General Physics and Astronomy,General Biochemistry, Genetics and Molecular Biology,General Chemistry
Reference56 articles.
1. Mokry, L. E. et al. Vitamin D and risk of multiple sclerosis: a mendelian randomization study. PLoS Med. 12, e1001866 (2015). 2. Rhead, B. et al. Mendelian randomization shows a causal effect of low vitamin D on multiple sclerosis risk. Neurol. Genet. 2, e97 (2016). 3. Martineau, A. R. et al. Vitamin D supplementation to prevent acute respiratory tract infections: systematic review and meta-analysis of individual participant data. Br. Med. J. 356, i6583 (2017). 4. Pilz, S., Verheyen, N., Grübler, M. R., Tomaschitz, A. & März, W. Vitamin D and cardiovascular disease prevention. Nat. Rev. Cardiol. 13, 404–417 (2016). 5. Garland, C. F. et al. The role of vitamin D in cancer prevention. Am. J. Public Health 96, 252–261 (2006).
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