Effect of specific non-pharmaceutical intervention policies on SARS-CoV-2 transmission in the counties of the United States
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Published:2021-06-11
Issue:1
Volume:12
Page:
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ISSN:2041-1723
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Container-title:Nature Communications
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language:en
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Short-container-title:Nat Commun
Author:
Yang BingyiORCID, Huang Angkana T.ORCID, Garcia-Carreras Bernardo, Hart William E., Staid Andrea, Hitchings Matt D. T., Lee Elizabeth C., Howe Chanelle J., Grantz Kyra H., Wesolowksi AmyORCID, Lemaitre Joseph ChadiORCID, Rattigan Susan, Moreno Carlos, Borgert Brooke A.ORCID, Dale Celeste, Quigley Nicole, Cummings Andrew, McLorg Alizée, LoMonaco Kaelene, Schlossberg Sarah, Barron-Kraus Drew, Shrock Harrison, Khoury Stephanie, Indra Meenal, Yau Hung-Leong, Cummings Ben, Giannas Peter, McLean Martha-Grace, Hubbard Ken, Saunders Camazia, Weldon Caroline, Phillips Caroline, Rosenbaum David, Tabla Dianelys, Lessler JustinORCID, Laird Carl D., Cummings Derek A. T.ORCID,
Abstract
AbstractNon-pharmaceutical interventions (NPIs) remain the only widely available tool for controlling the ongoing SARS-CoV-2 pandemic. We estimated weekly values of the effective basic reproductive number (Reff) using a mechanistic metapopulation model and associated these with county-level characteristics and NPIs in the United States (US). Interventions that included school and leisure activities closure and nursing home visiting bans were all associated with a median Reff below 1 when combined with either stay at home orders (median Reff 0.97, 95% confidence interval (CI) 0.58–1.39) or face masks (median Reff 0.97, 95% CI 0.58–1.39). While direct causal effects of interventions remain unclear, our results suggest that relaxation of some NPIs will need to be counterbalanced by continuation and/or implementation of others.
Publisher
Springer Science and Business Media LLC
Subject
General Physics and Astronomy,General Biochemistry, Genetics and Molecular Biology,General Chemistry
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