Homo-PROTACs: bivalent small-molecule dimerizers of the VHL E3 ubiquitin ligase to induce self-degradation-Reference-Cited by-同舟云学术

Homo-PROTACs: bivalent small-molecule dimerizers of the VHL E3 ubiquitin ligase to induce self-degradation

Published:2017-10-10 Issue:1 Volume:8 Page:
ISSN:2041-1723
Container-title:Nature Communications
language:en
Short-container-title:Nat Commun

Author:

Maniaci Chiara,Hughes Scott J.,Testa Andrea^ORCID,Chen Wenzhang,Lamont Douglas J.,Rocha Sonia^ORCID,Alessi Dario R.^ORCID,Romeo Roberto,Ciulli Alessio^ORCID

Publisher

Springer Science and Business Media LLC

Subject

General Physics and Astronomy,General Biochemistry, Genetics and Molecular Biology,General Chemistry

Link

http://www.nature.com/articles/s41467-017-00954-1.pdf

Reference75 articles.

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3. Galdeano, C. Drugging the undruggable: targeting challenging E3 ligases for personalized medicine. Future Med. Chem. 9, 347–350 (2017).

4. Morreale, F. E. & Walden, H. Types of ubiquitin ligases. Cell 165, 248–248.e1 (2016).

5. Zheng, N. & Shabek, N. Ubiquitin ligases: structure, function, and regulation. Annu. Rev. Biochem. 86, 129–157 (2017).

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