A systems biology approach uncovers cell-specific gene regulatory effects of genetic associations in multiple sclerosis
Author:
Publisher
Springer Science and Business Media LLC
Subject
General Physics and Astronomy,General Biochemistry, Genetics and Molecular Biology,General Chemistry
Link
http://www.nature.com/articles/s41467-019-09773-y.pdf
Reference52 articles.
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3. Maurano, M. T. et al. Systematic localization of common disease-associated variation in regulatory DNA. Science 337, 1190–1195 (2012).
4. Shooshtari, P., Huang, H. & Cotsapas, C. Integrative genetic and epigenetic analysis uncovers regulatory mechanisms of autoimmune disease. Am. J. Hum. Genet 101, 75–86 (2017).
5. Cantor, R. M., Lange, K. & Sinsheimer, J. S. Prioritizing GWAS results: a review of statistical methods and recommendations for their application. Am. J. Hum. Genet 86, 6–22 (2010).
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