Post-lockdown SARS-CoV-2 nucleic acid screening in nearly ten million residents of Wuhan, China

Author:

Cao Shiyi,Gan Yong,Wang Chao,Bachmann Max,Wei Shanbo,Gong Jie,Huang Yuchai,Wang Tiantian,Li Liqing,Lu Kai,Jiang Heng,Gong Yanhong,Xu Hongbin,Shen Xin,Tian Qingfeng,Lv Chuanzhu,Song FujianORCID,Yin Xiaoxv,Lu ZuxunORCID

Abstract

AbstractStringent COVID-19 control measures were imposed in Wuhan between January 23 and April 8, 2020. Estimates of the prevalence of infection following the release of restrictions could inform post-lockdown pandemic management. Here, we describe a city-wide SARS-CoV-2 nucleic acid screening programme between May 14 and June 1, 2020 in Wuhan. All city residents aged six years or older were eligible and 9,899,828 (92.9%) participated. No new symptomatic cases and 300 asymptomatic cases (detection rate 0.303/10,000, 95% CI 0.270–0.339/10,000) were identified. There were no positive tests amongst 1,174 close contacts of asymptomatic cases. 107 of 34,424 previously recovered COVID-19 patients tested positive again (re-positive rate 0.31%, 95% CI 0.423–0.574%). The prevalence of SARS-CoV-2 infection in Wuhan was therefore very low five to eight weeks after the end of lockdown.

Funder

The National Social Science Foundation of China

Publisher

Springer Science and Business Media LLC

Subject

General Physics and Astronomy,General Biochemistry, Genetics and Molecular Biology,General Chemistry

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