Oridonin is a covalent NLRP3 inhibitor with strong anti-inflammasome activity-Reference-Cited by-同舟云学术

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Oridonin is a covalent NLRP3 inhibitor with strong anti-inflammasome activity

Published:2018-06-29 Issue:1 Volume:9 Page:
ISSN:2041-1723
Container-title:Nature Communications
language:en
Short-container-title:Nat Commun

Author:

He Hongbin,Jiang Hua,Chen Yun,Ye Jin,Wang Aoli,Wang Chao^ORCID,Liu Qingsong^ORCID,Liang Gaolin^ORCID,Deng Xianming,Jiang Wei,Zhou Rongbin^ORCID

Funder

Ministry of Science and Technology of the People's Republic of China (Chinese Ministry of Science and Technology)

Chinese Academy of Sciences (CAS)

Publisher

Springer Science and Business Media LLC

Subject

General Physics and Astronomy,General Biochemistry, Genetics and Molecular Biology,General Chemistry

Link

http://www.nature.com/articles/s41467-018-04947-6.pdf

Reference61 articles.

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2. Kuo, L. M. et al. Intracellular glutathione depletion by oridonin leads to apoptosis in hepatic stellate cells. Molecules 19, 3327–3344 (2014).

3. Ding, Y. et al. Discovery and development of natural product oridonin-inspired anticancer agents. Eur. J. Med. Chem. 122, 102–117 (2016).

4. Fujita, E., Nagao, Y., Kaneko, K., Nakazawa, S. & Kuroda, H. The antitumor and antibacterial activity of the Isodon diterpenoids. Chem. Pharm. Bull. 24, 2118–2127 (1976).

5. Chen, S., Liu, J. & Zhang, H. Efficacy of rabdosia rubescens in the treatment of gingivitis. J. Huazhong Univ. Sci. Technol. Med. Sci. 29, 659–663 (2009).

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