Virus diversity, wildlife-domestic animal circulation and potential zoonotic viruses of small mammals, pangolins and zoo animals
-
Published:2023-04-29
Issue:1
Volume:14
Page:
-
ISSN:2041-1723
-
Container-title:Nature Communications
-
language:en
-
Short-container-title:Nat Commun
Author:
Cui Xinyuan, Fan KeweiORCID, Liang Xianghui, Gong Wenjie, Chen WuORCID, He Biao, Chen Xiaoyuan, Wang Hai, Wang Xiao, Zhang Ping, Lu Xingbang, Chen Rujian, Lin KaixiongORCID, Liu Jiameng, Zhai Junqiong, Liu Ding Xiang, Shan Fen, Li YuqiORCID, Chen Rui Ai, Meng Huifang, Li Xiaobing, Mi Shijiang, Jiang Jianfeng, Zhou NiuORCID, Chen Zujin, Zou Jie-Jian, Ge DeyanORCID, Yang QisenORCID, He Kai, Chen TengtengORCID, Wu Ya-Jiang, Lu HaoranORCID, Irwin David M.ORCID, Shen Xuejuan, Hu Yuanjia, Lu Xiaoman, Ding Chan, Guan Yi, Tu ChangchunORCID, Shen YongyiORCID
Abstract
AbstractWildlife is reservoir of emerging viruses. Here we identified 27 families of mammalian viruses from 1981 wild animals and 194 zoo animals collected from south China between 2015 and 2022, isolated and characterized the pathogenicity of eight viruses. Bats harbor high diversity of coronaviruses, picornaviruses and astroviruses, and a potentially novel genus of Bornaviridae. In addition to the reported SARSr-CoV-2 and HKU4-CoV-like viruses, picornavirus and respiroviruses also likely circulate between bats and pangolins. Pikas harbor a new clade of Embecovirus and a new genus of arenaviruses. Further, the potential cross-species transmission of RNA viruses (paramyxovirus and astrovirus) and DNA viruses (pseudorabies virus, porcine circovirus 2, porcine circovirus 3 and parvovirus) between wildlife and domestic animals was identified, complicating wildlife protection and the prevention and control of these diseases in domestic animals. This study provides a nuanced view of the frequency of host-jumping events, as well as assessments of zoonotic risk.
Funder
Department of Education of Guangdong Province National Natural Science Foundation of China
Publisher
Springer Science and Business Media LLC
Subject
General Physics and Astronomy,General Biochemistry, Genetics and Molecular Biology,General Chemistry,Multidisciplinary
Reference71 articles.
1. Jones, K. E. et al. Global trends in emerging infectious diseases. Nature 451, 990–993 (2008). 2. Allen, T. et al. Global hotspots and correlates of emerging zoonotic diseases. Nat. Commun. 8, 1124 (2017). 3. Gibb, R. et al. Zoonotic host diversity increases in human-dominated ecosystems. Nature 584, 398–402 (2020). 4. Calisher, C. H., Childs, J. E., Field, H. E., Holmes, K. V. & Schountz, T. Bats: important reservoir hosts of emerging viruses. Clin. Microbiol. Rev. 19, 531–545 (2006). 5. Hayman, D. T. Bats as viral reservoirs. Annu. Rev. Virol. 3, 77–99 (2016).
Cited by
7 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
|
|