Difluoromethylation of (hetero)aryl chlorides with chlorodifluoromethane catalyzed by nickel
Author:
Publisher
Springer Science and Business Media LLC
Subject
General Physics and Astronomy,General Biochemistry, Genetics and Molecular Biology,General Chemistry
Link
http://www.nature.com/articles/s41467-018-03532-1.pdf
Reference46 articles.
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3. Fujikawa, K., Fujioka, Y., Kobayashi, A. & Amii, H. A new method for aromatic difluoromethylation: copper-catalyzed cross-coupling and decarboxylation sequence from aryl iodides. Org. Lett. 13, 5560–5563 (2011).
4. Fier, P. S. & Hartwig, J. F. Copper-mediated difluoromethylation of aryl and vinyl iodides. J. Am. Chem. Soc. 134, 5524–5527 (2012).
5. Prakash, G. K. et al. Copper-mediated difluoromethylation of (hetero)aryl iodides and beta-styryl halides with tributyl(difluoromethyl)stannane. Angew. Chem. Int. Ed. 51, 12090–12094 (2012).
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