Abstract
AbstractSynthetic DNA is a growing alternative to electronic-based technologies in fields such as data storage, product tagging, or signal processing. Its value lies in its characteristic attributes, namely Watson-Crick base pairing, array synthesis, sequencing, toehold displacement and polymerase chain reaction (PCR) capabilities. In this review, we provide an overview of the most prevalent applications of synthetic DNA that could shape the future of information technology. We emphasize the reasons why the biomolecule can be a valuable alternative for conventional electronic-based media, and give insights on where the DNA-analog technology stands with respect to its electronic counterparts.
Publisher
Springer Science and Business Media LLC
Subject
General Physics and Astronomy,General Biochemistry, Genetics and Molecular Biology,General Chemistry,Multidisciplinary
Reference122 articles.
1. CompTIA. IT Industry Outlook 2021 Rebuilding for the Future. (2020).
2. Jämsä-Jounela, S. L. Future trends in process automation. IFAC Proc. 8, 1–10 (2007).
3. Sanderson, K. Automation: chemistry shoots for the Moon. Nature 568, 577–579 (2019).
4. Church, G. M., Gao, Y. & Kosuri, S. Next-generation digital information storage in DNA. Science 337, 1628 (2012). This work demonstrates the idea of DNA data storage and the potential within this novel technology on a 1 MB scale.
5. Grass, R. N., Heckel, R., Puddu, M., Paunescu, D. & Stark, W. J. Robust chemical preservation of digital information on DNA in silica with error-correcting codes. Angew. Chem.-Int. Ed. 54, 2552–2555 (2015). This work presents the first solution to error-correction codes by using inner and outer codes. It also presents methods for preserving DNA for thousands of years or more.
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