Antivirals and antiviral strategies
Author:
Publisher
Springer Science and Business Media LLC
Subject
General Immunology and Microbiology,Microbiology,Infectious Diseases
Link
http://www.nature.com/articles/nrmicro975.pdf
Reference126 articles.
1. De Clercq, E. Strategies in the design of antiviral drugs. Nature Rev. Drug Discov. 1, 13–25 (2002). Highlights the different mechanistic strategies that could be followed or envisaged towards the design and development of antiviral drugs.
2. De Clercq, E. Clinical potential of the acyclic nucleoside phosphonates cidofovir, adefovir, and tenofovir in treatment of DNA virus and retrovirus infections. Clin. Microbiol. Rev. 16, 569–596 (2003). Provides a comprehensive review of the clinical potential of three nucleotide analogues in the treatment of herpes-, pox-, adeno- and papillomavirus infections (cidofovir), HBV infections (adefovir) and HIV infections (tenofovir).
3. Andrei, G., Snoeck, R., Vandeputte, M. & De Clercq, E. Activities of various compounds against murine and primate polyomaviruses. Antimicrob. Agents Chemother. 41, 587–593 (1997).
4. Andrei, G., Snoeck, R., Schols, D. & De Clercq, E. Induction of apoptosis by cidofovir in human papillomavirus (HPV)-positive cells. Oncol. Res. 12, 397–408 (2001).
5. Abdulkarin, B. et al. Antiviral agent cidofovir restores p53 function and enhances the radiosensitivity in HPV-associated cancers. Oncogene 21, 2334–2346 (2002).
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