A rare mutation in UNC5C predisposes to late-onset Alzheimer's disease and increases neuronal cell death-Reference-Cited by-同舟云学术

A rare mutation in UNC5C predisposes to late-onset Alzheimer's disease and increases neuronal cell death

Published:2014-11-24 Issue:12 Volume:20 Page:1452-1457
ISSN:1078-8956
Container-title:Nature Medicine
language:en
Short-container-title:Nat Med

Author:

Wetzel-Smith Monica K, ,Hunkapiller Julie,Bhangale Tushar R,Srinivasan Karpagam,Maloney Janice A,Atwal Jasvinder K,Sa Susan M,B Yaylaoglu Murat,Foreman Oded,Ortmann Ward,Rathore Nisha,Hansen David V,Tessier-Lavigne Marc,Mayeux Richard,Pericak-Vance Margaret,Haines Jonathan,Farrer Lindsay A,Schellenberg Gerard D,Goate Alison,Behrens Timothy W,Cruchaga Carlos,Watts Ryan J,Graham Robert R

Publisher

Springer Science and Business Media LLC

Subject

General Biochemistry, Genetics and Molecular Biology,General Medicine

Link

http://www.nature.com/articles/nm.3736.pdf

Reference44 articles.

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3. Cruchaga, C. et al. Rare variants in APP, PSEN1 and PSEN2 increase risk for AD in late-onset Alzheimer's disease families. PLoS ONE 7, e31039 (2012).

4. Cruchaga, C. et al. Rare coding variants in the phospholipase D3 gene confer risk for Alzheimer's disease. Nature 505, 550–554 (2014).

5. Genin, E. et al. APOE and Alzheimer disease: a major gene with semi-dominant inheritance. Mol. Psychiatry 16, 903–907 (2011).

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