Siglec-9 acts as an immune-checkpoint molecule on macrophages in glioblastoma, restricting T-cell priming and immunotherapy response-Reference-Cited by-同舟云学术

Siglec-9 acts as an immune-checkpoint molecule on macrophages in glioblastoma, restricting T-cell priming and immunotherapy response

Published:2023-07-17 Issue:9 Volume:4 Page:1273-1291
ISSN:2662-1347
Container-title:Nature Cancer
language:en
Short-container-title:Nat Cancer

Author:

Mei Yan^ORCID,Wang Xiumei,Zhang Ji,Liu Dan,He Junjie,Huang Chunliu,Liao Jing,Wang Yingzhao,Feng Yongyi,Li Hongyu,Liu Xiuying,Chen Lingdan,Yi Wei,Chen Xi^ORCID,Bai Hong-Min,Wang Xinyu,Li Yiyi,Wang Lixiang,Liang Zhigang,Ren Xianwen,Qiu Li,Hui Yuan,Zhang Qingling^ORCID,Leng Qibin^ORCID,Chen Jun^ORCID,Jia Guangshuai^ORCID

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Oncology

Link

https://www.nature.com/articles/s43018-023-00598-9.pdf

Reference59 articles.

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3. Gustafson, M. P. et al. Systemic immune suppression in glioblastoma: the interplay between CD14+HLA-DRlo/neg monocytes, tumor factors, and dexamethasone. Neuro. Oncol. 12, 631–644 (2010).

4. Chongsathidkiet, P. et al. Sequestration of T cells in bone marrow in the setting of glioblastoma and other intracranial tumors. Nat. Med. 24, 1459–1468 (2018).

5. Cloughesy, T. F. et al. Neoadjuvant anti-PD-1 immunotherapy promotes a survival benefit with intratumoral and systemic immune responses in recurrent glioblastoma. Nat. Med. 25, 477–486 (2019).

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