Discovery of a first-in-class reversible DNMT1-selective inhibitor with improved tolerability and efficacy in acute myeloid leukemia
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Published:2021-09-27
Issue:10
Volume:2
Page:1002-1017
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ISSN:2662-1347
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Container-title:Nature Cancer
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language:en
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Short-container-title:Nat Cancer
Author:
Pappalardi Melissa B.ORCID, Keenan Kathryn, Cockerill Mark, Kellner Wendy A., Stowell Alexandra, Sherk Christian, Wong Kristen, Pathuri Sarath, Briand Jacques, Steidel Michael, Chapman Philip, Groy Arthur, Wiseman Ashley K., McHugh Charles F., Campobasso NinoORCID, Graves Alan P., Fairweather Emma, Werner Thilo, Raoof Ali, Butlin Roger J., Rueda Lourdes, Horton John R.ORCID, Fosbenner David T., Zhang Cunyu, Handler Jessica L., Muliaditan Morris, Mebrahtu Makda, Jaworski Jon-Paul, McNulty Dean E., Burt Charlotte, Eberl H. ChristianORCID, Taylor Amy N., Ho Thau, Merrihew Susan, Foley Shawn W., Rutkowska Anna, Li Mei, Romeril Stuart P., Goldberg Kristin, Zhang Xing, Kershaw Christopher S., Bantscheff MarcusORCID, Jurewicz Anthony J., Minthorn Elisabeth, Grandi Paola, Patel Mehul, Benowitz Andrew B., Mohammad Helai P., Gilmartin Aidan G., Prinjha Rab K.ORCID, Ogilvie Donald, Carpenter Christopher, Heerding Dirk, Baylin Stephen B., Jones Peter A.ORCID, Cheng XiaodongORCID, King Bryan W., Luengo Juan I., Jordan Allan M.ORCID, Waddell Ian, Kruger Ryan G., McCabe Michael T.ORCID
Funder
Cancer Research UK U.S. Department of Health & Human Services | National Institutes of Health Cancer Prevention and Research Institute of Texas U.S. Department of Health & Human Services | NIH | National Cancer Institute Van Andel Research Institute -Stand up to Cancer Epigenetics Dream Team. Stand Up to Cancer is a division of the Entertainment Industry Foundation, administered by AACR
Publisher
Springer Science and Business Media LLC
Subject
Cancer Research,Oncology
Reference67 articles.
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