Epigenetic targeted therapy of stabilized BAP1 in ASXL1 gain-of-function mutated leukemia
Author:
Funder
U.S. Department of Health & Human Services | NIH | National Cancer Institute
Publisher
Springer Science and Business Media LLC
Subject
Cancer Research,Oncology
Link
http://www.nature.com/articles/s43018-021-00199-4.pdf
Reference41 articles.
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2. Wang, L. et al. Resetting the epigenetic balance of Polycomb and COMPASS function at enhancers for cancer therapy. Nat. Med. 24, 758 (2018).
3. Wang, L. & Shilatifard, A. UTX mutations in human cancer. Cancer Cell 35, 168–176 (2019).
4. Morgan, M. A. & Shilatifard, A. Chromatin signatures of cancer. Genes Dev. 29, 238–249 (2015).
5. Rasmussen, K. D. & Helin, K. Role of TET enzymes in DNA methylation, development, and cancer. Gene Dev. 30, 733–750 (2016).
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