Molecular basis of inverse agonism in a G protein–coupled receptor
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cell Biology,Molecular Biology
Link
http://www.nature.com/articles/nchembio705z.pdf
Reference16 articles.
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3. Ghanouni, P. et al. Functionally different agonists induce distinct conformations in the G protein coupling domain of the β2 adrenergic receptor. J. Biol. Chem. 276, 24433–24436 (2001).
4. Sheikh, S.P. et al. Similar structures and shared switch mechanisms of the β2-adrenoceptor and the parathyroid hormone receptor. J. Biol. Chem. 274, 17033–17041 (1999).
5. Vilardaga, J.-P., Bünemann, M., Krasel, C., Castro, M. & Lohse, M. Measurement of the millisecond activation switch of G protein–coupled receptors in living cells. Nat. Biotechnol. 21, 807–812 (2003).
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