A synergistic small-molecule combination directly eradicates diverse prion strain structures-Reference-Cited by-同舟云学术

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A synergistic small-molecule combination directly eradicates diverse prion strain structures

Published:2009-11-01 Issue:12 Volume:5 Page:936-946
ISSN:1552-4450
Container-title:Nature Chemical Biology
language:en
Short-container-title:Nat Chem Biol

Author:

Roberts Blake E,Duennwald Martin L,Wang Huan,Chung Chan,Lopreiato Nicholas P,Sweeny Elizabeth A,Knight M Noelle,Shorter James

Publisher

Springer Science and Business Media LLC

Subject

Cell Biology,Molecular Biology

Link

http://www.nature.com/articles/nchembio.246.pdf

Reference50 articles.

1. Nelson, R. & Eisenberg, D. Structural models of amyloid-like fibrils. Adv. Protein Chem. 73, 235–282 (2006).

2. Skovronsky, D.M., Lee, V.M.-Y. & Trojanowski, J.Q. Neurodegenerative diseases: new concepts of pathogenesis and their therapeutic implications. Annu. Rev. Pathol. 1, 151–170 (2006).

3. Prusiner, S.B. Prions. Proc. Natl. Acad. Sci. USA 95, 13363–13383 (1998).

4. Roberts, B.E. & Shorter, J. Escaping amyloid fate. Nat. Struct. Mol. Biol. 15, 544–546 (2008).

5. Wells, J.A. & McClendon, C.L. Reaching for high-hanging fruit in drug discovery at protein-protein interfaces. Nature 450, 1001–1009 (2007).

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