utImmunohistochemical Detection of the Alternate INK4a-Encoded Tumor Suppressor Protein p14ARF in Archival Human Cancers and Cell Lines Using Commercial Antibodies: Correlation with p16INK4a Expression

Author:

Geradts Joseph,Wilentz Robb E,Roberts Helen

Publisher

Springer Science and Business Media LLC

Subject

Pathology and Forensic Medicine

Reference22 articles.

1. Stone S, Jiang P, Dayananth P, Tavtigian SV, Katcher H, Parry D, et al. Complex structure and regulation of the p16 (MTS1) locus. Cancer Res 1995; 55: 2988–2994.

2. Lukas J, Aagaard L, Strauss M, Bartek J . Oncogenic aberrations of p16INK4/CDKN2 and cyclin D1 cooperate to deregulate G1 control. Cancer Res 1995; 55: 4818–4823.

3. Liggett Jr WH, Sidransky D . Role of the p16 tumor suppressor gene in cancer. J Clin Oncol 1998; 16: 1197–1206.

4. Geradts J, Kratzke RA, Niehans GA, Lincoln CE . Immunohistochemical detection of the cyclin-dependent kinase inhibitor 2/multiple tumor suppressor gene 1 (CDKN2/MTS1) product p16INK4A in archival human solid tumors: correlation with retinoblastoma protein expression. Cancer Res 1995; 55: 6006–6011.

5. Geradts J, Hruban R, Schutte M, Kern S, Maynard R . Immunohistochemical p16INK4a analysis of archival tumors with deletion, hypermethylation, or mutation of the CDKN2/MTS1 gene: a comparison of four commercial antibodies. Appl Immunohistochem Mol Morphol 2000; 81: 71–79.

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