The von Hippel–Lindau tumour suppressor protein: O2 sensing and cancer
Author:
Publisher
Springer Science and Business Media LLC
Subject
General Earth and Planetary Sciences,General Environmental Science
Link
http://www.nature.com/articles/nrc2502.pdf
Reference145 articles.
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2. Tanimoto, K., Makino, Y., Pereira, T. & Poellinger, L. Mechanism of regulation of the hypoxia-inducible factor-1α by the von Hippel–Lindau tumor suppressor protein. EMBO J. 19, 4298–4309 (2000).
3. Cockman, M. et al. Hypoxia inducible factor-α binding and ubiquitylation by the von Hippel-Lindau tumor suppressor protein. J. Biol. Chem. 275, 25733–25741 (2000).
4. Kamura, T. et al. Activation of HIF1α ubiquitination by a reconstituted von Hippel–Lindau tumor suppressor complex. Proc. Natl Acad. Sci. USA 97, 10430–10435 (2000).
5. Ohh, M. et al. Ubiquitination of HIF requires direct binding to the von Hippel-Lindau protein β domain. Nature Cell Biol. 2, 423–427 (2000).
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