Single dose of a vaccine based on DNA encoding mycobacterial hsp65 protein plus TDM-loaded PLGA microspheres protects mice against a virulent strain of Mycobacterium tuberculosis-Reference-Cited by-同舟云学术

Single dose of a vaccine based on DNA encoding mycobacterial hsp65 protein plus TDM-loaded PLGA microspheres protects mice against a virulent strain of Mycobacterium tuberculosis

Published:2003-04 Issue:8 Volume:10 Page:678-685
ISSN:0969-7128
Container-title:Gene Therapy
language:en
Short-container-title:Gene Ther

Author:

Lima K M,Santos S A,Lima V M F,Coelho-Castelo A A M,Rodrigues J M,Silva C L

Publisher

Springer Science and Business Media LLC

Subject

Genetics,Molecular Biology,Molecular Medicine

Link

http://www.nature.com/articles/3301908.pdf

Reference30 articles.

1. World Health Organization. Global tuberculosis control. WHO Report 2001. Geneva, Switzerland, WHO/CDS/TB/2001.287.

2. Ginsberg AM . A proposed national strategy for tuberculosis vaccine development. Clin Infect Dis 2000; 30 (Suppl 3): S233-S242.

3. Enserink M . Driving a stake into resurgent TB. Science 2001; 293: 234-235.

4. Thomson J . New TB vaccine to be tested. Nat Med. 2001; 7: 1263.

5. Silva CL, Lowrie DB . A single mycobacterial protein (hsp65) expressed by a transgenic antigen-presenting cell vaccinates mice against tuberculosis. Immunology 1994; 82: 244–248.

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