Induction of immune tolerance to a transplantation carbohydrate antigen by gene therapy with autologous lymphocytes transduced with adenovirus containing the corresponding glycosyltransferase gene
Author:
Publisher
Springer Science and Business Media LLC
Subject
Genetics,Molecular Biology,Molecular Medicine
Link
http://www.nature.com/articles/3302178.pdf
Reference47 articles.
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2. Yang Y-G et al. Tolerization of anti-Galα1-3Gal natural antibody-forming B cells by induction of mixed chimerism. J Exp Med 1998; 187: 1335–1342.
3. Ohdan H et al. Mixed chimerism induced without lethal conditioning prevents T cell- and anti-Galα1,3Gal-mediated graft rejection. J Clin Invest 1999; 104: 281–290.
4. Bracy JL, Sachs DH, Iacomini J . Inhibition of xenoreactive natural antibody production by retroviral gene therapy. Science 1998; 281: 1845–1847.
5. Bracy JL, Iacomini J . Induction of B-cell tolerance by retroviral gene therapy. Blood 2000; 96: 3008–3015.
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1. Antibody production and tolerance to the α-gal epitope as models for understanding and preventing the immune response to incompatible ABO carbohydrate antigens and for α-gal therapies;Frontiers in Molecular Biosciences;2023-06-28
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